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| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Patient-Centered Pharmacotherapy | 65% | - Pathophysiology and clinical presentation - Pharmacokinetics and pharmacodynamics - Drug selection, dosing, and monitoring - Therapeutic guidelines and evidence-based treatment - Adverse drug reactions and interactions |
| Topic 2: Application of Evidence to Practice and Education | 25% | - Literature evaluation and biostatistics - Patient education and counseling - Clinical research and guideline development - Drug information and communication |
| Topic 3: Healthcare Systems and Population Health | 10% | - Regulatory and economic considerations - Healthcare delivery models - Medication safety and quality improvement - Population-based pharmacotherapy |
1. A patient presents to the emergency department with an acute Ischemic stroke. The symptoms have been present for just over an hour.
Which test would be most appropriate to help determine the patient's eligibility to receive t-PA?
A) Neurologic exam
B) CT scan
C) MRI
D) Cerebral angiogram
2. A 54-year-old male patient (BSA = 1.8 m2) is being treated for head and neck cancer with the following regimen:
* Cisplatin 100 mg/m2 intravenously on day 1
* 5-Fluorouracil 1000 mg/m2 intravenously by continuous infusion on days 1 through 5
* Ondansetron 16 mg intravenously
Which of the following is the appropriate administration instruction for ondansetron?
A) Thirty minutes before Cisplatin on day 1
B) Daily prior to 5-fluorouracil infusion on days 1 through 5
C) One dose 30 minutes before Cisplatin and a repeat dose immediately before 5- fluorouracil on day 1; then repeat daily before 5-fluorouracil
D) Thirty minutes prior to Cisplatin, thereafter as needed for nausea
3. In which of the following scenarios should the error be reported to the Institute for Safe Medication Practices?
A) A shipment of influenza vaccine was received by the pharmacy and was not placed in a refrigerator until the following day.
B) A pharmacy technician fills a prescription incorrectly with a "sound-alike" product, but the error is caught by the pharmacist before being dispensed to the patient.
C) A patient receives a 30-day supply of a prescription written for twice daily dosing with only 30 tablets dispensed.
D) A patient complains to a pharmacy manager that she did not receive an iPLEDGE brochure when receiving isotretinoin.
4. A patient with a nasogastric output of 8 L daily and respirations of 10 bpm has the following - laboratory values:
This clinical information is most consistent with which of the following?
A) Compensated respiratory alkalosis
B) Compensated metabolic alkalosis
C) Uncompensated metabolic alkalosis
D) Uncompensated respiratory alkalosis
5. A patient presents with palpitations and shortness of breath. A 12-lead ECG reveals a regular narrow QRS complex supraventricular tachycardia. What is the recommended first-line therapy?
A) Adenosine
B) Verapamil
C) Lidocaine
D) Amiodarone
Solutions:
| Question # 1 Answer: B | Question # 2 Answer: A | Question # 3 Answer: D | Question # 4 Answer: A | Question # 5 Answer: A |
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